| Protein Name |
Glyceraldehyde-3-phosphate dehydrogenase |
| #PDB ID |
1
|
| Organism |
Geobacillus stearothermophilus (Bacillus stearothermophilus) |
| Uniprot ID/ACC |
P00362 (G3P_GEOSE)
|
| Synonym(s) |
- type I glyceraldehyde-3-phosphate dehydrogenase
- D9549_RS06810
- D9549_06810
show 2 synonym(s)
|
| Gene Symbol |
gap
|
| Gene ID |
58573429
|
| Sequence |
MAVKVGINGFGRIGRNVFRAALKNPDIEVVAVNDLTDANTLAHLLKYDSVHGRLDAEVSVNGNNLVVNGKEIIVKAERDPENLAWGEIGVDIVVESTGRFTKREDAAKHLEAGAKKVIISAPAKNEDITIVMGVNQDKYDPKAHHVISNASCTTNCLAPFAKVLHEQFGIVRGMMTTVHSYTNDQRILDLPHKDLRRARAAAESIIPTTTGAAKAVALVLPELKGKLNGMAMRVPTPNVSVVDLVAELEKEVTVEEVNAALKAAAEGELKGILAYSEEPLVSRDYNGSTVSSTIDALSTMVIDGKMVKVVSWYDNETGYSHRVVDLAAYIASKGL |
| Protein Class |
OXIDOREDUCTASE |
| Function |
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
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