| Protein Name |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 |
| #PDB ID |
3
|
| Organism |
Homo sapiens (Human) |
| Uniprot ID/ACC |
O94760 (DDAH1_HUMAN)
|
| Synonym(s) |
- NG
- NG-dimethylarginine dimethylaminohydrolase
- dimethylargininase-1
- epididymis secretory protein Li 16
- DDAH
- DDAH-1
- DDAHI
- HEL-S-16
show 7 synonym(s)
|
| Gene Symbol |
DDAH1
|
| Gene ID |
23576
|
| Sequence |
MAGLGHPAAFGRATHAVVRALPESLGQHALRSAKGEEVDVARAERQHQLYVGVLGSKLGLQVVELPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS |
| Protein Class |
HYDROLASE |
| Function |
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
|
