Protein
Protein Name Orotidine 5'-phosphate decarboxylase
#PDB ID 5
Organism Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
Uniprot ID/ACC O26232 (PYRF_METTH)
Synonym(s) -
Gene Symbol pyrF
Gene ID -
Sequence MRSRRVDVMDVMNRLILAMDLMNRDDALRVTGEVREYIDTVKIGYPLVLSEGMDIIAEFRKRFGCRIIADFKVADIPETNEKICRATFKAGADAIIVHGFRGADSVRACLNVAEEMGREVFLLTEMSHPGAEMFIQGAADEIARMGVDLGVKNYVGPSTRPERLSRLREIIGQDSFLISPGVGAQGGDPGETLRFADAIIVGRSIYLADNPAAAAAGIIESIKDLLNP
Protein Class LYASE
Function Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
Bound Ligands
Ligand ID HET Code PDB ID Binding Affinity Binding Database Structure Complex Card
COVPDB302 6AZ 2ZZ6 Ki : 190 nM, Ki : 200 nM BindingDB SHOW
COVPDB307 6CN 2ZZ3 Ki : 29000 nM BindingDB SHOW
COVPDB307 6CN 2ZZ4 Ki : 29000 nM BindingDB SHOW
COVPDB263 5FU 3SGU
-
-
SHOW
COVPDB263 5FU 3SW6
-
-
SHOW