Protein
Protein Name Lon protease
#PDB ID 1
Organism Meiothermus taiwanensis
Uniprot ID/ACC A0A059VAZ3 (A0A059VAZ3_9DEIN)
Synonym(s) -
Gene Symbol lonA1
Gene ID -
Sequence MRLELPVIPLRNTVILPHTTTPVDVGRAKSKRAVEEAMGADRLIFLVAQRDPEVDDPAPDDLYTWGVQAVVKQAMRLPDGTLQVMVEARARAQVTDYIPGPYLRARGEVFSEIFPIDEAVVRVLVEELKEAFEKYVANHKSLRLDRYQLEAVKGTSDPAMLADTIAYHATWTVAEKQEILELTDLEARLKKVLGLLSRDLERFELDKRVAQRVKEQMDTNQREYYLREQMKAIQKELGGEDGLSDLEALRKKIEEVGMPEAVKTKALKELDRLERMQQGSPEATVARTYLDWLTEVPWSKADPEVLDINHTRQVLDEDHYGLKDVKERILEYLAVRQLTQGLDVRNKAPILVLVGPPGVGKTSLGRSIARSMNRKFHRISLGGVRDEAEIRGHRRTYIGAMPGKLIHAMKQVGVINPVILLDEIDKMSSDWRGDPASAMLEVLDPEQNNTFTDHYLDVPYDLSKVFFITTANTLQTIPRPLLDRMEVIEIPGYTNMEKQAIARQYLWPKQVRESGMEGRIEVTDAAILRVISEYTREAGVRGLERELGKIARKGAKFWLEGAWEGLRTIDASDIPTYLGIPRYRPDKAETEPQVGTAQGLAWTPVGGTLLTIEVAAVPGSGKLSLTGQLGEVMKESAQAALTYLRAHTQDYGLPEDFYNKVDLHVHVPDGATPKDGPSAGITMATAIASALSRRPARMDIAMTGEVSLRGKVMPIGGVKEKLLAAHQAGIHKIVLPKDNEAQLEELPKEVLEGLEIKLVEDVGEVLEYLLLPEPTMPPVVQPSDNRQQPGAGA
Protein Class HYDROLASE
Function ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
Bound Ligands
Ligand ID HET Code PDB ID Binding Affinity Binding Database Structure Complex Card
COVPDB574 BO2 4YPM
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