Ligand
Ligand Name:   CEFOPERAZONE
Ligand Type:   non-polymer
Ligand ID:   COVPDB253 PubChem:   44187
Synonym(s):  
  •   62893-19-0
  • cefobid
  • cefoperazono
  • cefoperazonum
  • cefoperazone acid
  • unii-7u75i1278d
  • cefoperazone (cefobid)
  • chebi:3493
  • (6r,7r)-7-((r)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • cefoperazine
  • mfcd00865067
  • 7u75i1278d
  • medocef
  • cefob
  • cefobid (tn)
  • cefoperazonum [inn-latin]
  • cefoperazono [inn-spanish]
  • (6r,7r)-7-((r)-2-(4-ethyl-2,3-dioxo-1-piperazinylcarboxamido)-2-(4-hydroxyphenyl)acetamido)-3-((1-methyl-1h-tetrazol-5-yl)thiomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure
  • cefoperazone (sodium salt)
  • cefozon
  • (6r,7r)-7-((r)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-((1-methyl-1h-tetrazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2r)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1h-tetrazol-5-yl)thio]methyl]-8-oxo-,(6r,7r)-
  • c25h27n9o8s2
  • 113826-44-1
  • cefoperazone [inn:ban]
  • bioperazone
  • cefoperazon
  • myticef
  • pathozone
  • cefoperazone,(s)
  • (6r,7r)-7-[[2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • einecs 263-749-4
  • cefoperazone (inn)
  • brn 0603333
  • cp 52640
  • prestwick0_000327
  • prestwick1_000327
  • prestwick2_000327
  • prestwick3_000327
  • peracef [veterinary] (tn)
  • schembl37056
  • bspbio_000333
  • bidd:gt0677
  • spbio_002254
  • bpbio1_000367
  • chembl507674
  • dtxsid2022759
  • hms2090m09
  • c25h31n9o10s2
  • hy-b0210
  • zinc3830432
  • bdbm50390999
  • s1611
  • akos015895629
  • ccg-270325
  • db01329
  • ncgc00179599-01
  • as-13298
  • h832
  • ab0013293
  • sw198793-3
  • y0421
  • c06883
  • d07645
  • 127501-ep2272832a1
  • 127501-ep2295402a2
  • 893c190
  • cefoperazone, antibiotic for culture media use only
  • q2325775
  • brd-k02292852-335-03-1
  • (6r,7r)-7-{[(2r)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetyl]amino}-3-{[(1-methyl-1h-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6r,7r)-7-{[(2r)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetyl]amino}-3-{[(1-methyl-1h-tetrazol-5-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((((4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl)amino)(4-hydroxyphenyl)acetyl)amino)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-, (6r-(6-alpha,7-beta(r*)))-
  • 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2r)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1h-tetrazol-5-yl)thio]methyl]-8-oxo-, (6r,7r)-
  • 7beta-{[(2r)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetyl]amino}-3-[(1-methyl-1h-tetrazol-5-yl)sulfanyl]methyl-3,4-didehydrocepham-4-carboxylic acid
  • sodium,(6r,7r)-7-[[(2r)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
show 75 synonym(s)
DrugBank:   DB01329 ChEMBL:   CHEMBL507674
Canonical SMILES:   CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(CSc4nnnn4C)=C(N3C2=O)C(O)=O)c2ccc(O)cc2)C(=O)C1=O
Standard InChI:   InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15-,16-,22-/m1/s1
Molecular Formula:   C25H27N9O8S2 Mol. Weight:   645.1424 logP:   -1.112
HBD:   4 HBA:   13
#Rotatable Bonds:   9 TPSA:   220.26

Bound Proteins
Protein Name Uniprot ID/ACC Organism PDB ID HET Code Binding Affinity Binding Database Complex Card
Peptidoglycan D,D-transpeptidase FtsI Q51504 (Q51504_PSEAI) Pseudomonas aeruginosa 5DF8 59F
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