Ligand
Ligand Name:   Tebipenem
Ligand Type:   non-polymer
Ligand ID:   COVPDB1383 PubChem:   9892071
Synonym(s):  
  •   tebipenem pivoxil
  • 161715-24-8
  • orapenem
  • tbpm-pi
  • l-084
  • me1211
  • unii-95ak1a52i8
  • ljc 11,084
  • 95ak1a52i8
  • ljc-11084
  • me-1211
  • 2,2-dimethylpropanoyloxymethyl (4r,5s,6s)-3-[1-(4,5-dihydro-1,3-thiazol-2-yl)azetidin-3-yl]sulfanyl-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
  • tebipenempivoxil
  • tebipenem [inn]
  • (4r,5s,6s)-(pivaloyloxy)methyl 3-((1-(4,5-dihydrothiazol-2-yl)azetidin-3-yl)thio)-6-((r)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
  • 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (4r,5s,6s)-
  • tebipenem pivoxil (l-084)
  • tebipenem pivoxil(l-084)
  • orapenem (tn)
  • (1r,5s,6s)-6-[1(r)-hydroxyethyl]-1-methyl-2-[1-(2-thiazolin-2-yl)azetidin-3-ylsulfanyl]-1-carba-2-penem-3-carboxylic acid pivaloyloxymethyl ester
  • mls006011128
  • schembl305541
  • tebipenem pivoxil [usan:inn]
  • chembl2107486
  • gtpl10864
  • dtxsid00167228
  • chebi:135799
  • ex-a1256
  • hy-b0396
  • who 7924
  • zinc4217736
  • tebipenem pivoxil (jan/usan/inn)
  • 2748ah
  • ct0255
  • ljc 11084
  • mfcd17215369
  • s2159
  • akos015899532
  • ccg-269673
  • ljc-11,084
  • ncgc00346570-01
  • ncgc00346570-04
  • (pivaloyloxy)methyl (4r,5s,6s)-3-((1-(4,5-dihydrothiazol-2-yl)azetidin-3-yl)thio)-6-((r)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
  • [(4r,5s,6s)-3-{[1-(4,5-dihydro-1,3-thiazol-2-yl)azetidin-3-yl]sulfanyl}-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carbonyloxy]methyl 2,2-dimethylpropanoate
  • ac-22712
  • as-75334
  • l-084;me1211
  • smr004702908
  • l 084
  • d09598
  • ab01566835_01
  • q1623593
  • (4r,5r,6s)-3-((1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl)thio)-6-((1r)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy) methyl ester
  • 2,2-dimethylpropanoyloxymethyl (4r,5s,6s)-3-[1-(4,5-dihydrothiazol-2-yl)azetidin-3-yl]sulfanyl-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
show 53 synonym(s)
DrugBank:   - ChEMBL:   CHEMBL2107486
Canonical SMILES:   CC(C)(C)C(=O)OCOC(=O)C1=C([C@H](C)[C@@H](N12)[C@H](C2=O)[C@@H](C)O)SC3CN(C3)C4=NCCS4
Standard InChI:   InChI=1S/C22H31N3O6S2/c1-11-15-14(12(2)26)18(27)25(15)16(19(28)30-10-31-20(29)22(3,4)5)17(11)33-13-8-24(9-13)21-23-6-7-32-21/h11-15,26H,6-10H2,1-5H3/t11-,12-,14-,15-/m1/s1
Molecular Formula:   C22H31N3O6S2 Mol. Weight:   497.16544 logP:   1.6657
HBD:   1 HBA:   10
#Rotatable Bonds:   6 TPSA:   108.74

Bound Proteins
Protein Name Uniprot ID/ACC Organism PDB ID HET Code Binding Affinity Binding Database Complex Card
Beta-lactamase P9WKD3 (BLAC_MYCTU) Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 4Q8I TEB
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