Protein

Download

Protein Name Protein arginine N-methyltransferase 5
#PDB ID 4
Organism Homo sapiens
Uniprot ID/ACC O14744 (ANM5_HUMAN)
Protein Sequence MAAMAVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL
Protein Class TRANSCRIPTION REGULATOR
Synonym(s)
  •   protein arginine N-methyltransferase 5
  • 72 kDa ICln-binding protein
  • HMT1 hnRNP methyltransferase-like 5
  • SKB1 homolog
  • histone-arginine N-methyltransferase PRMT5
  • jak-binding protein 1
  • shk1 kinase-binding protein 1 homolog
  • HRMT1L5
  • HSL7
  • IBP72
  • JBP1
  • SKB1
  • SKB1Hs
show 12 synonym(s)
Gene Symbol PRMT5
Gene ID 10419
Pfam ID PF05185, PF17286, PF17285
Interpro ID IPR025799, IPR007857, IPR035075, IPR035248, IPR035247, IPR029063
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
5QH Small Molecule 5EMK IC50 : 100.0 nM BindingDB SHOW
3XV Small Molecule 4X60 IC50 : 100.0 nM, IC50 : 22.0 nM BindingDB SHOW
3XV Small Molecule 4X60 Kd : 1.0 nM Binding MOAD SHOW
3XV Small Molecule 4X63 IC50 : 22.0 nM, IC50 : 100.0 nM BindingDB SHOW
5QJ Small Molecule 5EMJ IC50 : 33.0 nM Binding MOAD SHOW