Protein

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Protein Name Lysine-specific demethylase 4E
#PDB ID 1
Organism Homo sapiens
Uniprot ID/ACC B2RXH2 (KDM4E_HUMAN)
Protein Sequence MKSVHSSPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHQAGLAKVIPPKEWKARQMYDDIEDILIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRRLANSKKYQTPPHQNFADLEQRYWKSHPGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVALISPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGESTVTFSMDPFVRIVQPESYELWKHRQDLAIVEHTEPRVAESQELSNWRDDIVLRRAALGLRLLPNLTAQCPTQPVSSGHCYNPKGCGTDAVPGSAFQSSAYHTQTQSLTLGMSARVLLPSTGSWGSGRGRGRGQGQGRGCSRGRGHGCCTRELGTEEPTVQPASKRRLLMGTRSRAQGHRPQLPLANDLMTNLSL
Protein Class TRANSCRIPTION REGULATOR
Synonym(s)
  •   lysine-specific demethylase 4E
  • KDM4D-like protein
  • [histone H3]-trimethyl-L-lysine(9) demethylase 4E
  • lysine (K)-specific demethylase 4E
  • JMJD2E
  • KDM4DL
  • KDM5E
show 6 synonym(s)
Gene Symbol KDM4E
Gene ID 390245
Pfam ID PF02373, PF02375
Interpro ID IPR003347, IPR003349
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
PD2 Small Molecule 2W2I Ki : 914000.0 nM, IC50 : 1400.0 nM, IC50 : 6310.0 nM BindingDB SHOW