Ligand

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Ligand Name:   PYRIDINE-2,4-DICARBOXYLIC ACID
HET ID:   PD2 PubChem:   10365
DrugBank:   - ChEMBL:   CHEMBL316034
Canonical SMILES:   OC(=O)c1ccnc(c1)C(=O)O
Standard InChI:   InChI=1S/C7H5NO4/c9-6(10)4-1-2-8-5(3-4)7(11)12/h1-3H,(H,9,10)(H,11,12)
Molecular Formula:   C7H5NO4 Mol. Weight:   167.1189 Heavy Atoms:   12
Charge:   0 Is Chiral:   False logP:   0.478
HBD:   2 HBA:   5 TPSA:   87.49
#Bonds:   12 #Rotatable Bonds:   2 Shape Complexity:   0.0
Stereocomplexity:   0.0
Bound Proteins
Protein Name Uniprot ID/ACC Organism PDB ID Binding Affinity Binding Database Complex Card
Lysine-specific demethylase 4E B2RXH2 (KDM4E_HUMAN) Homo sapiens 2W2I Ki : 914000.0 nM, IC50 : 1400.0 nM, IC50 : 6310.0 nM BindingDB SHOW
Lysine-specific demethylase 4D Q6B0I6 (KDM4D_HUMAN) Homo sapiens 4D6Q
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