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Protein Download |
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| Protein Name | Squalene--hopene cyclase | |||||
|---|---|---|---|---|---|---|
| #PDB ID | 12 | |||||
| Organism | Alicyclobacillus acidocaldarius | |||||
| Uniprot ID/ACC | P33247 (SQHC_ALIAD) | |||||
| Protein Sequence | MAEQLVEAPAYARTLDRAVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHILDRVDRDRMEKIRRYLLHEQREDGTWALYPGGPPDLDTTIEAYVALKYIGMSRDEEPMQKALRFIQSQGGIESSRVFTRMWLALVGEYPWEKVPMVPPEIMFLGKRMPLNIYEFGSWARATVVALSIVMSRQPVFPLPERARVPELYETDVPPRRRGAKGGGGWIFDALDRALHGYQKLSVHPFRRAAEIRALDWLLERQAGDGSWGGIQPPWFYALIALKILDMTQHPAFIKGWEGLELYGVELDYGGWMFQASISPVWDTGLAVLALRAAGLPADHDRLVKAGEWLLDRQITVPGDWAVKRPNLKPGGFAFQFDNVYYPDVDDTAVVVWALNTLRLPDERRRRDAMTKGFRWIVGMQSSNGGWGAYDVDNTSDLPNHIPFCDFGEVTDPPSEDVTAHVLECFGSFGYDDAWKVIRRAVEYLKREQKPDGSWFGRWGVNYLYGTGAVVSALKAVGIDTREPYIQKALDWVEQHQNPDGGWGEDCRSYEDPAYAGKGASTPSQTAWALMALIAGGRAESEAARRGVQYLVETQRPDGGWDEPYYTGTGFPGDFYLGYTMYRHVFPTLALGRYKQAIERR | |||||
| Protein Class | ISOMERASE | |||||
| Synonym(s) | - | |||||
| Gene Symbol | - | |||||
| Gene ID | - | |||||
| Pfam ID | PF13243, PF13249 | |||||
| Interpro ID | IPR006400, IPR032696, IPR032697, IPR018333, IPR002365, IPR008930 |
Bound Ligands |
HET ID | Ligand Type | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
| R04 | Small Molecule | 1H3A | IC50 : 281.0 nM | PDBBind |  |
SHOW |
| R04 | Small Molecule | 1H3A | IC50 : 281.0 nM | BindingDB | |
SHOW |
| R71 | Small Molecule | 1GSZ | IC50 : 61.0 nM | PDBBind |  |
SHOW |
| R71 | Small Molecule | 1GSZ | IC50 : 61.0 nM | BindingDB | |
SHOW |
| R01 | Small Molecule | 1H35 | IC50 : 29.0 nM | PDBBind |  |
SHOW |
| R01 | Small Molecule | 1H35 | IC50 : 29.0 nM | BindingDB | |
SHOW |
| R88 | Small Molecule | 1H36 | IC50 : 18.0 nM | PDBBind |  |
SHOW |
| R88 | Small Molecule | 1H36 | IC50 : 18.0 nM | BindingDB | |
SHOW |
| R02 | Small Molecule | 1H37 | IC50 : 59.0 nM | PDBBind |  |
SHOW |
| R02 | Small Molecule | 1H37 | IC50 : 59.0 nM | BindingDB | |
SHOW |
| R03 | Small Molecule | 1H39 | IC50 : 289.0 nM | PDBBind |  |
SHOW |
| R03 | Small Molecule | 1H39 | IC50 : 289.0 nM | BindingDB | |
SHOW |
| R17 | Small Molecule | 1O6Q | IC50 : 23.0 nM | PDBBind |  |
SHOW |
| R17 | Small Molecule | 1O6Q | IC50 : 23.0 nM | BindingDB | |
SHOW |
| R19 | Small Molecule | 1O6R | IC50 : 80.0 nM | PDBBind |  |
SHOW |
| R19 | Small Molecule | 1O6R | IC50 : 80.0 nM | BindingDB | |
SHOW |
| R23 | Small Molecule | 1O79 | IC50 : 406.0 nM | PDBBind |  |
SHOW |
| R23 | Small Molecule | 1O79 | IC50 : 406.0 nM | BindingDB | |
SHOW |
| R79 | Small Molecule | 1H3C | IC50 : 306.0 nM | PDBBind |  |
SHOW |
| R79 | Small Molecule | 1H3C | IC50 : 306.0 nM | BindingDB | |
SHOW |
| R46 | Small Molecule | 1H3B | IC50 : 141.0 nM | PDBBind |  |
SHOW |
| R46 | Small Molecule | 1H3B | IC50 : 141.0 nM | BindingDB | |
SHOW |
| SQA | Small Molecule | 1UMP |
- |
- |
 |
SHOW |