Protein

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Protein Name cAMP-specific 3',5'-cyclic phosphodiesterase 4D
#PDB ID 3
Organism Homo sapiens
Uniprot ID/ACC Q08499 (PDE4D_HUMAN)
Protein Sequence MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPPLPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
Protein Class HYDROLASE
Synonym(s)
  •   cAMP-specific phosphodiesterase PDE4D6
  • phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)
  • testicular tissue protein Li 136
  • ACRDYS2
  • DPDE3
  • HSPDE4D
  • PDE43
  • PDE4DN2
  • STRK1
show 8 synonym(s)
Gene Symbol PDE4D
Gene ID 5144
Pfam ID PF18100, PF00233
Interpro ID IPR003607, IPR040844, IPR023088, IPR002073, IPR036971, IPR023174
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
ROL Small Molecule 1OYN IC50 : 550.0 nM PDBBind SHOW
ROL Small Molecule 1OYN IC50 : 550.0 nM Binding MOAD SHOW
0MO Small Molecule 3K4S
-
-
SHOW
IBM Small Molecule 1ZKN
-
-
SHOW