Protein

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Protein Name Arginase-1
#PDB ID 6
Organism Homo sapiens
Uniprot ID/ACC P05089 (ARGI1_HUMAN)
Protein Sequence MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK
Protein Class HYDROLASE
Synonym(s)
  •   arginase-1
  • arginase, liver
  • liver-type arginase
  • type I arginase
show 3 synonym(s)
Gene Symbol ARG1
Gene ID 383
Pfam ID PF00491
Interpro ID IPR014033, IPR006035, IPR023696, IPR020855
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
GPA Small Molecule 4FCI Ki : 55000000.0 nM PDBBind SHOW
GPA Small Molecule 4FCK Ki : 55000000.0 nM PDBBind SHOW
NNH Small Molecule 3KV2 Kd : 47.0 nM, Kd : 2000.0 nM BindingDB SHOW
NNH Small Molecule 3KV2 Kd : 47.51 nM Binding MOAD SHOW
HAR Small Molecule 3LP7 Kd : 3600.0 nM PDBBind SHOW
HAR Small Molecule 3LP7 Kd : 3600.0 nM Binding MOAD SHOW
LYS Small Molecule 3LP4 Kd : 13100.0 nM PDBBind SHOW
LYS Small Molecule 3LP4 Kd : 13100.0 nM Binding MOAD SHOW
DMO Small Molecule 3GN0 Ki : 3900000.0 nM Binding MOAD SHOW