Ligand

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Ligand Name:   5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide
HET ID:   RIV PubChem:   9875401
DrugBank:   DB06228 ChEMBL:   CHEMBL198362
Canonical SMILES:   O=C1O[C@H](CN1c1ccc(cc1)N1CCOCC1=O)CNC(=O)c1ccc(s1)Cl
Standard InChI:   InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1
Molecular Formula:   C19H18ClN3O5S Mol. Weight:   435.88132 Heavy Atoms:   29
Charge:   0 Is Chiral:   True logP:   3.0408
HBD:   1 HBA:   9 TPSA:   116.42
#Bonds:   33 #Rotatable Bonds:   6 Shape Complexity:   0.31578946
Stereocomplexity:   0.05263158
Bound Proteins
Protein Name Uniprot ID/ACC Organism PDB ID Binding Affinity Binding Database Complex Card
Coagulation factor X P00742 (FA10_HUMAN) Homo sapiens 2W26 Ki : 0.66 nM, Ki : 0.4 nM, Ki : 1.6 nM, Ki : 8.5 nM, Ki : 0.7 nM, Ki : 2.2 nM, Ki : 4.59 nM, Ki : 400.0 nM, Ki : 1.4 nM, Ki : 14.0 nM, Ki : 700.0 nM BindingDB SHOW
Coagulation factor X P00742 (FA10_HUMAN) Homo sapiens 2W26 Ki : 0.4 nM Binding MOAD SHOW