| Protein Name |
Peptidylarginine deiminase |
| #PDB ID |
1
|
| Organism |
Porphyromonas gingivalis (strain ATCC BAA-308 / W83) |
| Uniprot ID/ACC |
Q9RQJ2 (PAD_PORGI)
|
| Synonym(s) |
- peptidylarginine deiminase PPAD
- PGN_RS04285
- PGN_0898
show 2 synonym(s)
|
| Gene Symbol |
PG_1424
|
| Gene ID |
29256112
|
| Sequence |
MKKLLQAKALILALGLFQLPAIAQTQMQADRTNGQFATEEMQRAFQETNPPAGPVRAIAEYERSAAVLVRYPFGIPMELIKELAKNDKVITIVASESQKNTVITQYTQSGVNLSNCDFIIAKTDSYWTRDYTGWFAMYDTNKVGLVDFIYNRPRPNDDEFPKYEAQYLGIEMFGMKLKQTGGNYMTDGYGSAVQSHIAYTENSSLSQAQVNQKMKDYLGITHHDVVQDPNGEYINHVDCWGKYLAPNKILIRKVPDNHPQHQALEDMAAYFAAQTCAWGTKYEVYRALATNEQPYTNSLILNNRVFVPVNGPASVDNDALNVYKTAMPGYEIIGVKGASGTPWLGTDALHCRTHEVADKGYLYIKHYPILGEQAGPDYKIEADVVSCANATISPVQCYYRINGSGSFKAADMTMESTGHYTYSFTGLNKNDKVEYYISAADNSGRKETYPFIGEPDPFKFTCMNETNTCTVTGAAKALRAWFNAGRSELAVSVSLNIAGTYRIKLYNTAGEEVAAMTKELVAGTSVFSMDVYSQAPGTYVLVVEGNGIRETMKILK |
| Protein Class |
HYDROLASE |
| Function |
Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth.
|
