| Protein Name |
Methyl-branched alkylpyrone synthesis polyketide synthase-like Pks11 |
| #PDB ID |
3
|
| Organism |
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| Uniprot ID/ACC |
P9WPF3 (PKS11_MYCTU)
|
| Synonym(s) |
- type III polyketide synthase
- MCAN_RS08770
- MCAN_16731
show 2 synonym(s)
|
| Gene Symbol |
pks11
|
| Gene ID |
45425634
|
| Sequence |
MSVIAGVFGALPPHRYSQSEITDSFVEFPGLKEHEEIIRRLHAAAKVNGRHLVLPLQQYPSLTDFGDANEIFIEKAVDLGVEALLGALDDANLRPSDIDMIATATVTGVAVPSLDARIAGRLGLRPDVRRMPLFGLGCVAGAAGVARLRDYLRGAPDDVAVLVSVELCSLTYPAVKPTVSSLVGTALFGDGAAAVVAVGDRRAEQVRAGGPDILDSRSSLYPDSLHIMGWDVGSHGLRLRLSPDLTNLIERYLANDVTTFLDAHRLTKDDIGAWVSHPGGPKVIDAVATSLALPPEALELTWRSLGEIGNLSSASILHILRDTIEKRPPSGSAGLMLAMGPGFCTELVLLRWR |
| Protein Class |
TRANSFERASE |
| Function |
Involved in the biosynthesis of methyl-branched alkylpyrones (PubMed:23615910). Pks11 catalyzes the extension of medium- and long-chain aliphatic acyl-CoA substrates by using malonyl-CoA and methylmalonyl-CoA as extender molecules to synthesize polyketide products (PubMed:12941968, PubMed:23615910). Palmitoyl-CoA or a similar long chain fatty acid derivative is the likely substrate in vivo (PubMed:23615910).
|
