Protein
Protein Name 4-hydroxy-tetrahydrodipicolinate synthase
#PDB ID 1
Organism Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Uniprot ID/ACC P9WP25 (DAPA_MYCTU)
Synonym(s)
  •   MCAN_RS14585
  • MCAN_27801
show 1 synonym(s)
Gene Symbol dapA
Gene ID 45426740
Sequence MTTVGFDVAARLGTLLTAMVTPFSGDGSLDTATAARLANHLVDQGCDGLVVSGTTGESPTTTDGEKIELLRAVLEAVGDRARVIAGAGTYDTAHSIRLAKACAAEGAHGLLVVTPYYSKPPQRGLQAHFTAVADATELPMLLYDIPGRSAVPIEPDTIRALASHPNIVGVKDAKADLHSGAQIMADTGLAYYSGDDALNLPWLAMGATGFISVIAHLAAGQLRELLSAFGSGDIATARKINIAVAPLCNAMSRLGGVTLSKAGLRLQGIDVGDPRLPQVAATPEQIDALAADMRAASVLR
Protein Class LYASE
Function Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
Bound Ligands
Ligand ID HET Code PDB ID Binding Affinity Binding Database Structure Complex Card
COVPDB310 6GT 5J5D IC50 : 21000 nM PDBBind SHOW