| Protein Name |
Thiazole synthase |
| #PDB ID |
1
|
| Organism |
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| Uniprot ID/ACC |
P9WG73 (THIG_MYCTU)
|
| Synonym(s) |
|
| Gene Symbol |
thiG
|
| Gene ID |
886396
|
| Sequence |
MAESKLVIGDRSFASRLIMGTGGATNLAVLEQALIASGTELTTVAIRRVDADGGTGLLDLLNRLGITPLPNTAGSRSAAEAVLTAQLAREALNTNWVKLEVIADERTLWPDAVELVRAAEQLVDDGFVVLPYTTDDPVLARRLEDTGCAAVMPLGSPIGTGLGIANPHNIEMIVAGARVPVVLDAGIGTASDAALAMELGCDAVLLASAVTRAADPPAMAAAMAAAVTAGYLARCAGRIPKRFWAQASSPAR |
| Protein Class |
TRANSFERASE |
| Function |
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H2S.
|
