Protein |
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Protein Name | Hemoglobin subunit beta | |||||
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#PDB ID | 2 | |||||
Organism | Homo sapiens (Human) | |||||
Uniprot ID/ACC | P68871 (HBB_HUMAN) | |||||
Synonym(s) |
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Gene Symbol | HBB | |||||
Gene ID | 3043 | |||||
Sequence | MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH | |||||
Protein Class | TRANSPORTER | |||||
Function | Involved in oxygen transport from the lung to the various peripheral tissues. LVV-hemorphin-7 potentiates the activity of bradykinin, causing a decrease in blood pressure. Spinorphin: functions as an endogenous inhibitor of enkephalin-degrading enzymes such as DPP3, and as a selective antagonist of the P2RX3 receptor which is involved in pain signaling, these properties implicate it as a regulator of pain and inflammation. |
Bound Ligands |
Ligand ID | HET Code | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
COVPDB748 | EBJ | 6BWU |
- |
- |
SHOW | |
COVPDB835 | G7Z | 6HK2 |
- |
- |
SHOW |