| Protein Name |
14-3-3 protein zeta/delta |
| #PDB ID |
1
|
| Organism |
Homo sapiens (Human) |
| Uniprot ID/ACC |
P63104 (1433Z_HUMAN)
|
| Synonym(s) |
- 14-3-3 delta
- 14-3-3 protein/cytosolic phospholipase A2
- 14-3-3 zeta
- epididymis luminal protein 4
- epididymis secretory protein Li 3
- epididymis secretory protein Li 93
- phospholipase A2
- protein kinase C inhibitor protein-1
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein
- delta polypeptide
- zeta polypeptide
- tyrosine 3/tryptophan 5 -monooxygenase activation protein
- 14-3-3-zeta
- HEL-S-3
- HEL-S-93
- HEL4
- KCIP-1
- POPCHAS
- YWHAD
show 18 synonym(s)
|
| Gene Symbol |
YWHAZ
|
| Gene ID |
7534
|
| Sequence |
MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN |
| Protein Class |
SIGNALING PROTEIN |
| Function |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation (PubMed:16959763). In neurons, regulates spine maturation through the modulation of ARHGEF7 activity (By similarity).
|
