Protein Name |
Retinal dehydrogenase 1 |
#PDB ID |
2
|
Organism |
Ovis aries (Sheep) |
Uniprot ID/ACC |
P51977 (AL1A1_SHEEP)
|
Synonym(s) |
- ALDH-E1
- ALHDII
- RALDH 1
- aldehyde dehydrogenase family 1 member A1
- aldehyde dehydrogenase
- cytosolic
- ralDH1
show 6 synonym(s)
|
Gene Symbol |
ALDH1A1
|
Gene ID |
443343
|
Sequence |
MSSSAMPDVPAPLTNLQFKYTKIFINNEWHSSVSGKKFPVFNPATEEKLCEVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLIERDRLLLATMEAMNGGKLFSNAYLMDLGGCIKTLRYCAGWADKIQGRTIPMDGNFFTYTRSEPVGVCGQIIPWNFPLLMFLWKIGPALSCGNTVVVKPAEQTPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVGKLIKEAAGKSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCCIAASRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYEKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGIFTNDIDKAITVSSALQSGTVWVNCYSVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTIKISQKNS |
Protein Class |
OXIDOREDUCTASE |
Function |
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (PubMed:26373694).
|