Protein
Protein Name Alpha-aminoadipic semialdehyde dehydrogenase
#PDB ID 1
Organism Homo sapiens (Human)
Uniprot ID/ACC P49419 (AL7A1_HUMAN)
Synonym(s)
  •   26g turgor protein homolog
  • P6c dehydrogenase
  • alpha-AASA dehydrogenase
  • antiquitin-1
  • betaine aldehyde dehydrogenase
  • delta1-piperideine-6-carboxylate dehydrogenase
  • epididymis secretory sperm binding protein
  • ATQ1
  • EPD
  • PDE
show 9 synonym(s)
Gene Symbol ALDH7A1
Gene ID 501
Sequence MWRLPRALCVHAAKTSKLSGPWSRPAAFMSTLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
Protein Class OXIDOREDUCTASE
Function Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism.
Bound Ligands
Ligand ID HET Code PDB ID Binding Affinity Binding Database Structure Complex Card
COVPDB207 3W9 4X0T
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