Protein
Protein Name Palmitoyl-protein thioesterase 1
#PDB ID 1
Organism Bos taurus (Bovine)
Uniprot ID/ACC P45478 (PPT1_BOVIN)
Synonym(s)
  •   PPT-1
  • palmitoyl protein thioesterase
  • palmitoyl-protein hydrolase 1
  • palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis
  • neuronal 1
  • infantile)
  • CLN1
show 6 synonym(s)
Gene Symbol PPT1
Gene ID 281421
Sequence MASSSCLWLLALAFLLGSCASLALGHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIHVLSLEIGKTLREDVENSFFLNVNSQVTTVCQILAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMVNLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYNKAIQERLVQAEYWHDPIREDIYRNHSIFLADINQERGVNESYKKNLMALKKFVMVKFLNDTIVDPVDSEWFGFYRSGQAKETIPLQESTLYTQDRLGLKAMDKAGQLVFLALEGDHLQLSEEWFYAHIIPFLE
Protein Class HYDROLASE
Function Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.
Bound Ligands
Ligand ID HET Code PDB ID Binding Affinity Binding Database Structure Complex Card
COVPDB900 HDS 1EXW Ki : 125000 nM PDBBind SHOW