| Protein Name |
Glyceraldehyde-3-phosphate dehydrogenase A |
| #PDB ID |
1
|
| Organism |
Escherichia coli (strain K12) |
| Uniprot ID/ACC |
P0A9B2 (G3P1_ECOLI)
|
| Synonym(s) |
- glyceraldehyde-3-phosphate dehydrogenase
- AJR21_RS15175
- AJR21_015375
show 2 synonym(s)
|
| Gene Symbol |
gapA
|
| Gene ID |
58462327
|
| Sequence |
MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK |
| Protein Class |
OXIDOREDUCTASE |
| Function |
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
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