Protein Name |
Phospholipase A1 |
#PDB ID |
1
|
Organism |
Escherichia coli (strain K12) |
Uniprot ID/ACC |
P0A921 (PA1_ECOLI)
|
Synonym(s) |
- phospholipase A
- AJR21_RS14280
- AJR21_014490
show 2 synonym(s)
|
Gene Symbol |
pldA
|
Gene ID |
58462159
|
Sequence |
MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYLIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGYNHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLKIGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLNDLF |
Protein Class |
TRANSFERASE |
Function |
Has broad substrate specificity including hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Strong expression leads to outer membrane breakdown and cell death; is dormant in normal growing cells. Required for efficient secretion of bacteriocins.
|