| Protein Name |
Glutathione S-transferase P |
| #PDB ID |
1
|
| Organism |
Homo sapiens (Human) |
| Uniprot ID/ACC |
P09211 (GSTP1_HUMAN)
|
| Synonym(s) |
- GST class-pi
- GSTP1-1
- deafness
- X-linked 7
- epididymis secretory protein Li 22
- fatty acid ethyl ester synthase III
- DFN7
- FAEES3
- GST3
- GSTP
- HEL-S-22
- PI
show 11 synonym(s)
|
| Gene Symbol |
GSTP1
|
| Gene ID |
2950
|
| Sequence |
MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ |
| Protein Class |
HYDROLASE |
| Function |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276). Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
|
