Protein |
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Protein Name | Cathepsin G | |||||
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#PDB ID | 2 | |||||
Organism | Homo sapiens (Human) | |||||
Uniprot ID/ACC | P08311 (CATG_HUMAN) | |||||
Synonym(s) |
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Gene Symbol | CTSG | |||||
Gene ID | 1511 | |||||
Sequence | MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL | |||||
Protein Class | HYDROLASE | |||||
Function | Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride. |
Bound Ligands |
Ligand ID | HET Code | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
COVPDB101 | 1ZG | 1CGH |
- |
- |
SHOW | |
COVPDB19 | 0H8 | 1AU8 |
- |
- |
SHOW |