Protein
Protein Name Carbonic anhydrase 2
#PDB ID 4
Organism Homo sapiens (Human)
Uniprot ID/ACC P00918 (CAH2_HUMAN)
Synonym(s)
  •   carbonate dehydratase II
  • carbonic anhydrase B
  • carbonic anhydrase C
  • carbonic anhydrase II
  • carbonic dehydratase
  • epididymis luminal protein 76
  • epididymis secretory protein Li 282
  • CA-II
  • CAC
  • CAII
  • Car2
  • HEL-76
  • HEL-S-282
show 12 synonym(s)
Gene Symbol CA2
Gene ID 760
Sequence MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
Protein Class LYASE
Function Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.
Bound Ligands
Ligand ID HET Code PDB ID Binding Affinity Binding Database Structure Complex Card
COVPDB681 DAW 3KNE
-
-
SHOW
COVPDB554 BFE 3M2Z
-
-
SHOW
COVPDB555 BFG 3M5T
-
-
SHOW
COVPDB679 DA9 3KIG
-
-
SHOW