Protein Name |
Carbonic anhydrase 2 |
#PDB ID |
4
|
Organism |
Homo sapiens (Human) |
Uniprot ID/ACC |
P00918 (CAH2_HUMAN)
|
Synonym(s) |
- carbonate dehydratase II
- carbonic anhydrase B
- carbonic anhydrase C
- carbonic anhydrase II
- carbonic dehydratase
- epididymis luminal protein 76
- epididymis secretory protein Li 282
- CA-II
- CAC
- CAII
- Car2
- HEL-76
- HEL-S-282
show 12 synonym(s)
|
Gene Symbol |
CA2
|
Gene ID |
760
|
Sequence |
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK |
Protein Class |
LYASE |
Function |
Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.
|