Protein Name |
Retinal dehydrogenase 1 |
#PDB ID |
1
|
Organism |
Homo sapiens (Human) |
Uniprot ID/ACC |
P00352 (AL1A1_HUMAN)
|
Synonym(s) |
- ALDH class 1
- ALHDII
- RALDH 1
- acetaldehyde dehydrogenase 1
- aldehyde dehydrogenase 1
- soluble
- aldehyde dehydrogenase
- liver cytosolic
- epididymis luminal protein 12
- epididymis luminal protein 9
- epididymis secretory sperm binding protein Li 53e
- retinaldehyde dehydrogenase 1
- ALDC
- ALDH-E1
- ALDH1
- ALDH11
- HEL-9
- HEL-S-53e
- HEL12
- PUMB1
- RALDH1
show 20 synonym(s)
|
Gene Symbol |
ALDH1A1
|
Gene ID |
216
|
Sequence |
MSSSGTPDLPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS |
Protein Class |
OXIDOREDUCTASE |
Function |
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (PubMed:19296407, PubMed:26373694, PubMed:25450233).
|