Protein |
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| Protein Name | Peptidoglycan D,D-transpeptidase FtsI | |||||
|---|---|---|---|---|---|---|
| #PDB ID | 13 | |||||
| Organism | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | |||||
| Uniprot ID/ACC | G3XD46 (FTSI_PSEAE) | |||||
| Synonym(s) |
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| Gene Symbol | ftsI | |||||
| Gene ID | 881247 | |||||
| Sequence | MKLNYFQGALYPWRFCVIVGLLLAMVGAIVWRIVDLHVIDHDFLKGQGDARSVRHIAIPAHRGLITDRNGEPLAVSTPVTTLWANPKELMTAKERWPQLAAALGQDTKLFADRIEQNAEREFIYLVRGLTPEQGEGVIALKVPGVYSIEEFRRFYPAGEVVAHAVGFTDVDDRGREGIELAFDEWLAGVPGKRQVLKDRRGRVIKDVQVTKNAKPGKTLALSIDLRLQYLAHRELRNALLENGAKAGSLVIMDVKTGEILAMTNQPTYNPNNRRNLQPAAMRNRAMIDVFEPGSTVKPFSMSAALASGRWKPSDIVDVYPGTLQIGRYTIRDVSRNSRQLDLTGILIKSSNVGISKIAFDIGAESIYSVMQQVGLGQDTGLGFPGERVGNLPNHRKWPKAETATLAYGYGLSVTAIQLAHAYAALANDGKSVPLSMTRVDRVPDGVQVISPEVASTVQGMLQQVVEAQGGVFRAQVPGYHAAGKSGTARKVSVGTKGYRENAYRSLFAGFAPATDPRIAMVVVIDEPSKAGYFGGLVSAPVFSKVMAGALRLMNVPPDNLPTATEQQQVNAAPAKGGRG | |||||
| Protein Class | HYDROLASE | |||||
| Function | Catalyzes cross-linking of the peptidoglycan cell wall at the division septum (By similarity). Binds penicillin (PubMed:20580675). |
Bound Ligands |
Ligand ID | HET Code | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
| COVPDB994 | JPP | 4KQO | IC50 : 166 nM | PDBBind |  |
SHOW |
| COVPDB994 | JPP | 6R42 |
- |
- |
|
SHOW |
| COVPDB1412 | UE1 | 3PBT |
- |
- |
 |
SHOW |
| COVPDB1178 | ODZ | 6Y6U |
- |
- |
 |
SHOW |
| COVPDB1139 | NEF | 6HR9 |
- |
- |
 |
SHOW |
| COVPDB942 | IM2 | 3PBQ |
- |
- |
 |
SHOW |
| COVPDB994 | JPP | 6R3X |
- |
- |
|
SHOW |
| COVPDB724 | MER | 3PBR |
- |
- |
 |
SHOW |
| COVPDB1275 | RB6 | 6VJE |
- |
- |
 |
SHOW |
| COVPDB1388 | TJ7 | 6UN1 |
- |
- |
 |
SHOW |
| COVPDB1471 | XT8 | 6UN3 |
- |
- |
 |
SHOW |
| COVPDB624 | CAZ | 3PBO |
- |
- |
 |
SHOW |
| COVPDB1179 | OEE | 6Y6Z |
- |
- |
 |
SHOW |