| Protein Name |
N-acetylneuraminate lyase |
| #PDB ID |
2
|
| Organism |
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) |
| Uniprot ID/ACC |
P44539 (NANA_HAEIN)
|
| Synonym(s) |
-
|
| Gene Symbol |
nanA
|
| Gene ID |
-
|
| Sequence |
MRDLKGIFSALLVSFNEDGTINEKGLRQIIRHNIDKMKVDGLYVGGSTGENFMLSTEEKKEIFRIAKDEAKDQIALIAQVGSVNLKEAVELGKYATELGYDCLSAVTPFYYKFSFPEIKHYYDTIIAETGNNMIVYSIPFLTGVNMGIEQFGELYKNPKVLGVKFTAGDFYLLERLKKAYPNHLIWAGFDEMMLPAASLGVDGAIGSTFNVNGVRARQIFELTKAGKLAEALEIQHVTNDLIEGILANGLYLTIKELLKLEGVDAGYCREPMTSKATEEQLAKAKDLKAKFLS |
| Protein Class |
LYASE |
| Function |
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
|
