Protein |
||||||
| Protein Name | Acetylcholinesterase | |||||
|---|---|---|---|---|---|---|
| #PDB ID | 11 | |||||
| Organism | Tetronarce californica (Pacific electric ray) (Torpedo californica) | |||||
| Uniprot ID/ACC | P04058 (ACES_TETCF) | |||||
| Synonym(s) | - | |||||
| Gene Symbol | ache | |||||
| Gene ID | - | |||||
| Sequence | MNLLVTSSLGVLLHLVVLCQADDHSELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNATACDGELSSSGTSSSKGIIFYVLFSILYLIF | |||||
| Protein Class | HYDROLASE | |||||
| Function | Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions. |
Bound Ligands |
Ligand ID | HET Code | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
| COVPDB786 | FBQ | 1HBJ | IC50 : 3 nM | PDBBind |  |
SHOW |
| COVPDB786 | FBQ | 1HBJ | IC50 : 11000 nM | BindingDB | |
SHOW |
| COVPDB877 | GSG | 2BAG | IC50 : 5120 nM | BindingDB |  |
SHOW |
| COVPDB851 | GD8 | 2WG2 |
- |
- |
 |
SHOW |
| COVPDB1452 | VX | 1VXR |
- |
- |
 |
SHOW |
| COVPDB761 | EMM | 1GQR |
- |
- |
 |
SHOW |
| COVPDB481 | ACH | 2ACE |
- |
- |
 |
SHOW |
| COVPDB628 | CCD | 2VJC |
- |
- |
 |
SHOW |
| COVPDB628 | CCD | 2VJA |
- |
- |
|
SHOW |
| COVPDB851 | GD8 | 2WFZ |
- |
- |
|
SHOW |
| COVPDB628 | CCD | 2VJD |
- |
- |
|
SHOW |
| COVPDB628 | CCD | 2VJB |
- |
- |
|
SHOW |