Protein |
||||||
| Protein Name | Cathepsin B | |||||
|---|---|---|---|---|---|---|
| #PDB ID | 2 | |||||
| Organism | Rattus norvegicus (Rat) | |||||
| Uniprot ID/ACC | P00787 (CATB_RAT) | |||||
| Synonym(s) | - | |||||
| Gene Symbol | Ctsb | |||||
| Gene ID | - | |||||
| Sequence | MWWSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGPNLPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHCGIESEIVAGIPRTQQYWGRF | |||||
| Protein Class | HYDROLASE | |||||
| Function | Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (PubMed:1639824). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). |
Bound Ligands |
Ligand ID | HET Code | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
| COVPDB13 | 0E6 | 1THE |
- |
- |
 |
SHOW |
| COVPDB1247 | PYS | 1CTE |
- |
- |
 |
SHOW |