Ligand
Ligand Name:   6-thioguanine
Ligand Type:   non-polymer
Ligand ID:   COVPDB725 PubChem:   2723601
Synonym(s):  
  •   thioguanine
  • 154-42-7
  • tioguanine
  • 2-amino-6-mercaptopurine
  • 6-mercaptoguanine
  • tioguanin
  • tabloid
  • lanvis
  • 2-amino-6-purinethiol
  • 2-amino 6mp
  • 2-aminopurin-6-thiol
  • 2-aminopurine-6-thiol
  • 2-aminopurine-6(1h)-thione
  • wellcome u3b
  • 6-mercapto-2-aminopurine
  • 2-amino-9h-purine-6-thiol
  • 6-tg
  • 2-amino-6-merkaptopurin
  • tioguaninum
  • guanine, thio-
  • tioguanina
  • 6h-purine-6-thione, 2-amino-1,7-dihydro-
  • 2-amino-1,7-dihydro-6h-purine-6-thione
  • bw 5071
  • purine-6-thiol, 2-amino-
  • purine-6(1h)-thione, 2-amino-
  • 2-amino-1,9-dihydro-6h-purine-6-thione
  • nsc-752
  • tg
  • c5h5n5s
  • thg
  • nsc 752
  • 2-amino-1,7-dihydro-6h-purin-6-thion
  • x 27
  • unii-wix31zpx66
  • tioguanine (inn)
  • 9h-purine-6-thiol, 2-amino-
  • 2-amino-1,9-dihydropurine-6-thione
  • mfcd00233553
  • chembl727
  • wix31zpx66
  • 2-amino-6,7-dihydro-3h-purine-6-thione
  • chebi:9555
  • nsc752
  • thioguanine2-amino-6-purinethiol
  • 2-thioguanine
  • tioguanine [inn]
  • 2-amino-1,7-dihydropurine-6-thione
  • ncgc00094792-01
  • dsstox_cid_3652
  • 2-amino-6-mp
  • 2-amino-3,7-dihydropurine-6-thione
  • dsstox_rid_77129
  • dsstox_gsid_23652
  • tioguaninum [inn-latin]
  • 2-aminopurin-6-thiol [czech]
  • guanine, thio- (van)
  • 2-amino-6-merkaptopurin [czech]
  • 6-tioguanine
  • tioguanina [inn-spanish]
  • cas-154-42-7
  • dx4
  • smr000857244
  • lanvis (tn)
  • thioguanine anhydrous
  • ccris 8997
  • nsc-76504
  • hsdb 2504
  • sr-05000002077
  • einecs 205-827-2
  • thioguanine [usan:usp]
  • 2-amino-1,7-dihydro-6h-purin-6-thion [czech]
  • thioquanine
  • ai3-26078
  • 7h-purine-6-thiol, 2-amino-
  • 6-thioguano-sine
  • 6-tg/thioguanine
  • tioguanine hemihydrate
  • pubchem9185
  • thioguanine, anhydrous
  • 6-thioguanine/6-tg
  • 1h-purine-6-thiol, 2-amino- (9ci)
  • spectrum_000235
  • acmc-209dan
  • spectrum2_000695
  • spectrum3_000577
  • spectrum4_000926
  • spectrum5_001455
  • purine antimetabolite: antimetabolite: inhibits nucleic acid replication
  • 2-amino-6-mercapto-purin
  • 6-thioguanine, >=98%
  • schembl3701
  • schembl5898
  • nciopen2_004153
  • bspbio_001994
  • kbiogr_001452
  • kbiogr_002476
  • kbioss_000715
  • kbioss_002483
  • mls001333131
  • mls001333132
  • mls006010896
  • divk1c_000428
  • spectrum1500573
  • 6h-purine-6-thione, 2-amino-3,7-dihydro- (9ci)
  • spbio_000849
  • 154-42-7|6-thioguanine
  • 2-amino-6-mercapto-9h-purine
  • gtpl6845
  • thioguanine (tn) (glaxosmith)
  • dtxsid6023652
  • hms501f10
  • kbio1_000428
  • kbio2_000715
  • kbio2_002476
  • kbio2_003283
  • kbio2_005044
  • kbio2_005851
  • kbio2_007612
  • kbio3_001494
  • kbio3_002954
  • cmap_000061
  • ninds_000428
  • bcpe000001
  • hms1921e09
  • hms2092m11
  • hms2235f05
  • hms3865g13
  • pharmakon1600-01500573
  • 2-amino-1h-purine-6(9h)-thione
  • albb-023493
  • bcp27718
  • zinc6382803
  • tox21_111035
  • tox21_113184
  • tox21_202401
  • tox21_300275
  • abp000905
  • anw-21501
  • bdbm50200099
  • ccg-39890
  • nsc757348
  • s1774
  • sbb067147
  • akos003389499
  • akos015901298
  • tox21_111035_1
  • 2-amino-1,7-dihydro-purine-6-thione
  • 2-amino-1,9-dihydro-purine-6-thione
  • ac-8421
  • bcp9000197
  • ccg-213953
  • ccg-266338
  • cs-1497
  • db00352
  • mcule-5787306636
  • nsc-757348
  • ps-5007
  • vz33872
  • wln: t56 bnm fym inj fus hz
  • idi1_000428
  • smp2_000326
  • ncgc00094792-02
  • ncgc00094792-03
  • ncgc00094792-05
  • ncgc00094792-06
  • ncgc00188976-01
  • ncgc00188976-02
  • ncgc00254082-01
  • ncgc00259950-01
  • ncgc00263442-01
  • ncgc00263442-05
  • 153981-51-2
  • 153981-52-3
  • 154034-61-4
  • 154034-62-5
  • ac-23020
  • h351
  • hy-13765
  • nci60_041643
  • smr004701808
  • sbi-0051533.p003
  • ab0013003
  • ft-0611217
  • r2215
  • st45025337
  • y7662
  • 2-amino-1,7-dihydro-6h-purine-6-thione #
  • c07648
  • d08603
  • j10163
  • w-5092
  • 15151-ep2275420a1
  • 15151-ep2295055a2
  • 15151-ep2295416a2
  • 15151-ep2295426a1
  • 15151-ep2295427a1
  • 15151-ep2298748a2
  • 15151-ep2298764a1
  • 15151-ep2298765a1
  • 15151-ep2305642a2
  • 15151-ep2308833a2
  • 15151-ep2311453a1
  • 15151-ep2311808a1
  • 15151-ep2311825a1
  • 15151-ep2311829a1
  • 15151-ep2311840a1
  • 15151-ep2311842a2
  • 15151-ep2316832a1
  • 15151-ep2316833a1
  • ab00174074_06
  • ab00918694_06
  • ab01273926-01
  • ab01273926-02
  • ab01273926_03
  • 120118-ep2270008a1
  • 120118-ep2272827a1
  • 120118-ep2292617a1
  • 120118-ep2298778a1
  • 154t427
  • q385347
  • sr-05000002077-1
  • sr-05000002077-5
  • w-108030
  • w-205813
  • z2768769146
  • 6-thioguanine;6-tg;2-amino-6-mercaptopurine;2-amino-6-purinethiol
  • thioguanine, united states pharmacopeia (usp) reference standard
  • thioguanine;6-tg; 2-amino-6-mercaptopurine; 2-amino-6-purinethiol
  • 6-thioguanine, hybri-max(tm), 50 x, gamma-irradiated, lyophilized powder, bioxtra, suitable for hybridoma
show 229 synonym(s)
DrugBank:   DB00352 ChEMBL:   CHEMBL727
Canonical SMILES:   S=c1[nH]c(N)nc(c12)nc[nH]2
Standard InChI:   InChI=1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
Molecular Formula:   C5H5N5S Mol. Weight:   167.02657 logP:   0.59769
HBD:   3 HBA:   4
#Rotatable Bonds:   0 TPSA:   83.38

Bound Proteins
Protein Name Uniprot ID/ACC Organism PDB ID HET Code Binding Affinity Binding Database Complex Card
Ubiquitin carboxyl-terminal hydrolase 2 O75604 (UBP2_HUMAN) Homo sapiens (Human) 5XU8 DX4
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