Ligand
Ligand Name:   [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl 4-ethyl-3-fluorosulfonyl-benzoate
Ligand Type:   non-polymer
Ligand ID:   COVPDB446 PubChem:   137348832
Synonym(s):   -
DrugBank:   - ChEMBL:   -
Canonical SMILES:   CCc1ccc(cc1S(=O)(=O)F)C(=O)OC[C@@H]2[C@@H](O)[C@@H](O)[C@@H](O2)n3cnc(c34)c(N)ncn4
Standard InChI:   InChI=1S/C19H20FN5O7S/c1-2-9-3-4-10(5-12(9)33(20,29)30)19(28)31-6-11-14(26)15(27)18(32-11)25-8-24-13-16(21)22-7-23-17(13)25/h3-5,7-8,11,14-15,18,26-27H,2,6H2,1H3,(H2,21,22,23)/t11-,14-,15-,18-/m1/s1
Molecular Formula:   C19H20FN5O7S Mol. Weight:   481.10675 logP:   0.1053
HBD:   3 HBA:   12
#Rotatable Bonds:   6 TPSA:   179.75

Bound Proteins
Protein Name Uniprot ID/ACC Organism PDB ID HET Code Binding Affinity Binding Database Complex Card
Fibroblast growth factor receptor 1 P11362 (FGFR1_HUMAN) Homo sapiens (Human) 5O4A 9K8
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