Ligand
Ligand Name:   N-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-5-yl}-2-(prop-2-enamido)benzamide
Ligand Type:   non-polymer
Ligand ID:   COVPDB433 PubChem:   139554482
Synonym(s):  
  •   chembl4284069
  • schembl21430886
show 1 synonym(s)
DrugBank:   - ChEMBL:   CHEMBL4284069
Canonical SMILES:   COc1cc(cc(c1)OC)CCc2cc([nH]n2)NC(=O)c3ccccc3NC(=O)C=C
Standard InChI:   InChI=1S/C23H24N4O4/c1-4-22(28)24-20-8-6-5-7-19(20)23(29)25-21-13-16(26-27-21)10-9-15-11-17(30-2)14-18(12-15)31-3/h4-8,11-14H,1,9-10H2,2-3H3,(H,24,28)(H2,25,26,27,29)
Molecular Formula:   C23H24N4O4 Mol. Weight:   420.17975 logP:   3.5889
HBD:   3 HBA:   5
#Rotatable Bonds:   9 TPSA:   105.34

Bound Proteins
Protein Name Uniprot ID/ACC Organism PDB ID HET Code Binding Affinity Binding Database Complex Card
Fibroblast growth factor receptor 4 P22455 (FGFR4_HUMAN) Homo sapiens (Human) 5NWZ 9CT Kd : 0.8 nM PDBBind SHOW