Ligand
Ligand Name:   6-diazo-5-oxo-l-norleucine
Ligand Type:   L-peptide linking
Ligand ID:   COVPDB410 PubChem:   9087
Synonym(s):  
  •   157-03-9
  • diazooxonorleucine
  • l-don
  • unii-03j0h273kz
  • (s)-2-amino-6-diazo-5-oxocaproic acid
  • 6-diazo-5-oxo-l-nor-leucine
  • 03j0h273kz
  • nsc-7365
  • mfcd00037218
  • (s)-2-amino-6-diazo-5-oxohexanoic acid
  • don (pharmaceutical)
  • l-norleucine, 6-diazo-5-oxo-
  • nsc 7365
  • l-6-diazo-5-oxonorleucine
  • brn 1725815
  • nsc7365
  • ai3-26441
  • l-norleucine,6-diazo-5-oxo-
  • norleucine, 6-diazo-5-oxo, l-
  • (2s)-2-amino-6-diazo-5-oxohexanoic acid
  • ncimech_000302
  • ncistruc1_000220
  • ncistruc2_000175
  • (l)-don
  • 4-04-00-03278 (beilstein handbook reference)
  • chembl97485
  • chembl4303391
  • schembl15349013
  • schembl15349015
  • kmx-010
  • nci7365
  • chebi:138889
  • (z,5s)-5-amino-1-diazonio-6-hydroxy-6-oxohex-1-en-2-olate
  • ex-a1965
  • zinc3953825
  • 5984ah
  • ccg-35449
  • ccg-37571
  • ncgc00013078
  • akos030213039
  • l-norleucine, 6-diazo-5-oxo- (9ci)
  • ncgc00013078-02
  • ncgc00096202-01
  • 6-diazo-5-oxo-l-norleucine, crystalline
  • hy-108357
  • (2s)-2-amino-6-diazo-5-oxo-hexanoic acid
  • cs-0028442
  • 77996-ep2277868a1
  • 77996-ep2277869a1
  • 77996-ep2277870a1
  • 77996-ep2308866a1
  • q245487
  • j-009370
  • unii-los90ik8xh component ycwqamgasjsuip-yfkpbyrvsa-n
show 53 synonym(s)
DrugBank:   - ChEMBL:   CHEMBL97485
Canonical SMILES:   N[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O
Standard InChI:   InChI=1S/C6H9N3O3/c7-5(6(11)12)2-1-4(10)3-9-8/h3,5H,1-2,7H2,(H,11,12)/t5-/m0/s1
Molecular Formula:   C6H9N3O3 Mol. Weight:   171.06439 logP:   -0.9518
HBD:   2 HBA:   3
#Rotatable Bonds:   5 TPSA:   116.79

Bound Proteins
Protein Name Uniprot ID/ACC Organism PDB ID HET Code Binding Affinity Binding Database Complex Card
Glutathione hydrolase 1 proenzyme P19440 (GGT1_HUMAN) Homo sapiens (Human) 5V4Q 8WY Ki : 2700000 nM PDBBind SHOW
Glutaminase kidney isoform, mitochondrial O94925 (GLSK_HUMAN) Homo sapiens (Human) 4O7D ONL IC50 : 1000000 nM PDBBind SHOW
Amidophosphoribosyltransferase P0AG16 (PUR1_ECOLI) Escherichia coli (strain K12) 1ECC ONL
-
-
SHOW
Glutaminase-asparaginase P10182 (ASPQ_PSES7) Pseudomonas sp. (strain ATCC 29598 / 7A) 1DJP DO2
-
-
SHOW
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] P17169 (GLMS_ECOLI) Escherichia coli (strain K12) 2J6H ONL
-
-
SHOW
Glutaminase 1 O31465 (GLSA1_BACSU) Bacillus subtilis (strain 168) 3BRM ONL
-
-
SHOW
Glutamine-dependent NAD(+) synthetase P9WJJ3 (NADE_MYCTU) Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 3DLA ONL
-
-
SHOW
Asparagine synthetase [glutamine-hydrolyzing] P08243 (ASNS_HUMAN) Homo sapiens (Human) 6GQ3 ONL
-
-
SHOW
L-asparaginase P06608 (ASPG_DICCH) Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi) 1JSR LDO
-
-
SHOW
Gamma-glutamyltranspeptidase Q65KZ6 (Q65KZ6_BACLD) Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46) 5Y9B DON
-
-
SHOW
Amidophosphoribosyltransferase P0AG16 (PUR1_ECOLI) Escherichia coli (strain K12) 1ECG ONL
-
-
SHOW
Ferredoxin-dependent glutamate synthase 2 P55038 (GLTS_SYNY3) Synechocystis sp. (strain PCC 6803 / Kazusa) 1OFE ONL
-
-
SHOW