Ligand
Ligand Name:   2-[(4R)-4-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(1,5-dihydroxy-4-oxopyridin-2-yl)methoxy]imino}acetamido]-3-oxo-1,2-oxazolidin-2-yl]-5-oxooxolane-2-carboxylic acid
Ligand Type:   non-polymer
Ligand ID:   COVPDB154 PubChem:   -
Synonym(s):   -
DrugBank:   - ChEMBL:   -
Canonical SMILES:   Nc1nc(cs1)C(=N\OCc1cc(=O)c(O)cn1[O-])\C(=O)N[C@@H]1CON(C1=O)[C@@]1(CCC(=O)O1)C(O)=O
Standard InChI:   InChI=1S/C19H17N6O11S/c20-18-22-10(7-37-18)14(23-34-5-8-3-11(26)12(27)4-24(8)33)15(29)21-9-6-35-25(16(9)30)19(17(31)32)2-1-13(28)36-19/h3-4,7,9,27H,1-2,5-6H2,(H2,20,22)(H,21,29)(H,31,32)/q-1/b23-14-/t9-,19-/m1/s1
Molecular Formula:   C19H17N6O11S- Mol. Weight:   537.0682 logP:   -1.7641
HBD:   4 HBA:   15
#Rotatable Bonds:   8 TPSA:   248.03

Bound Proteins
Protein Name Uniprot ID/ACC Organism PDB ID HET Code Binding Affinity Binding Database Complex Card
Cell division protein FtsI [Peptidoglycan synthetase] None (None) Pseudomonas aeruginosa 4OOL 2U2 IC50 : 140 nM PDBBind SHOW