PDB Entry (1g93) |
||
| ||
PDB ID: 1g93 | Resolution: 2.5 Å | Exp. Method: X-RAY DIFFRACTION |
PMID: 11179209 | DOI: 10.1093/emboj/20.4.638 | |
Protein |
|
Protein Name: N-acetyllactosaminide alpha-1,3-galactosyltransferase | |
Uniprot ID/ACC: P14769 (GGTA1_BOVIN) | Organism: Bos taurus (Bovine) |
Gene Symbol: GGTA1 | Gene ID: 281780 |
Protein Class: TRANSFERASE |
Ligand |
||
Ligand Name: beta-D-galactopyranose | ||
Canonical SMILES: OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](O1)O | ||
Standard InChI: InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6-/m1/s1 | ||
HET Code: GAL | PubChem: 439353 | |
DrugBank: - | ChEMBL: CHEMBL300520 | |
Molecular Formula: C6H12O6 | Mol. Weight: 180.06339 | logP: -3.2214 |
HBD: 5 | HBA: 6 | |
#Rotatable Bonds: 1 | TPSA: 110.38 |
Covalent Mechanism |
Reaction Name | Residue | Chain ID | SASA | pKa | Warhead Name | Warhead Structure |
Nucleophilic Acyl Substitution | GLU 317 | A | 26.91 | 9.64 | Hemiacetal |
Binding Affinity |
||
- |