Protein Download |
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Protein Name | TP53-binding protein 1 | |||||
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#PDB ID | 16 | |||||
Organism | Homo sapiens | |||||
Uniprot ID/ACC | Q12888 (TP53B_HUMAN) | |||||
Protein Sequence | MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPAKRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH | |||||
Protein Class | TRANSCRIPTION REGULATOR | |||||
Synonym(s) |
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Gene Symbol | TP53BP1 | |||||
Gene ID | 7158 | |||||
Pfam ID | PF09038 | |||||
Interpro ID | IPR015125, IPR001357, IPR036420, IPR014722 |
Bound Ligands |
HET ID | Ligand Type | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
K6S | Small Molecule | 6MXZ | IC50 : 14000.0 nM | BindingDB | SHOW | |
K6P | Small Molecule | 6MXX | IC50 : 13000.0 nM | BindingDB | SHOW | |
K6M | Small Molecule | 6MXY | IC50 : 22000.0 nM | BindingDB | SHOW | |
3OO | Small Molecule | 4RG2 | Kd : 22000.0 nM, Kd : 29000.0 nM, Kd : 30000.0 nM | BindingDB | SHOW | |
MLY | p53K370me2 | 2MWP |
- |
- |
SHOW | |
MLY | p53K370me2 | 2MWO |
- |
- |
SHOW | |
QSS | Small Molecule | 6VA5 |
- |
- |
SHOW | |
QXY | Small Molecule | 6VIP |
- |
- |
SHOW | |
MLY | p53-K382me2 | 3LGL |
- |
- |
SHOW | |
MLY | H4K20me2 | 2LVM |
- |
- |
SHOW | |
QFM | Small Molecule | 6UPT |
- |
- |
SHOW | |
MLY | p53-K370me2 | 3LGF |
- |
- |
SHOW | |
MLY | p53-K372me2 | 3LH0 |
- |
- |
SHOW | |
MLY | Rb-K810me2 | 4CRI |
- |
- |
SHOW | |
MLY | H4K20me2 | 2IG0 |
- |
- |
SHOW | |
MLY | p53-K381acK382me2 | 4X34 |
- |
- |
SHOW |