Protein

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Protein Name NAD-dependent protein deacetylase sirtuin-2
#PDB ID 1
Organism Homo sapiens
Uniprot ID/ACC Q8IXJ6 (SIR2_HUMAN)
Protein Sequence MAEPDPSHPLETQAGKVQEAQDSDSDSEGGAAGGEADMDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ
Protein Class TRANSCRIPTION REGULATOR
Synonym(s)
  •   NAD-dependent deacetylase sirtuin-2
  • SIR2-like protein 2
  • regulatory protein SIR2 homolog 2
  • silent information regulator 2
  • sir2-related protein type 2
  • sirtuin type 2
  • SIR2
  • SIR2L
  • SIR2L2
show 8 synonym(s)
Gene Symbol SIRT2
Gene ID 22933
Pfam ID PF02146
Interpro ID IPR029035, IPR003000, IPR026591, IPR017328, IPR026590
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
7KJ Small Molecule 5MAT IC50 : 580.0 nM Binding MOAD SHOW