Protein Download |
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Protein Name | Histone-lysine N-methyltransferase EHMT2 | |||||
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#PDB ID | 2 | |||||
Organism | Homo sapiens | |||||
Uniprot ID/ACC | Q96KQ7 (EHMT2_HUMAN) | |||||
Protein Sequence | MAAAAGAAAAAAAEGEAPAEMGALLLEKETRGATERVHGSLGDTPRSEETLPKATPDSLEPAGPSSPASVTVTVGDEGADTPVGATPLIGDESENLEGDGDLRGGRILLGHATKSFPSSPSKGGSCPSRAKMSMTGAGKSPPSVQSLAMRLLSMPGAQGAAAAGSEPPPATTSPEGQPKVHRARKTMSKPGNGQPPVPEKRPPEIQHFRMSDDVHSLGKVTSDLAKRRKLNSGGGLSEELGSARRSGEVTLTKGDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRKRRKREPPRAKEPRGVNGVGSSGPSEYMEVPLGSLELPSEGTLSPNHAGVSNDTSSLETERGFEELPLCSCRMEAPKIDRISERAGHKCMATESVDGELSGCNAAILKRETMRPSSRVALMVLCETHRARMVKHHCCPGCGYFCTAGTFLECHPDFRVAHRFHKACVSQLNGMVFCPHCGEDASEAQEVTIPRGDGVTPPAGTAAPAPPPLSQDVPGRADTSQPSARMRGHGEPRRPPCDPLADTIDSSGPSLTLPNGGCLSAVGLPLGPGREALEKALVIQESERRKKLRFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLGVGNRAIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQSRLARLDPHPELLPELGSLPPVNT | |||||
Protein Class | TRANSCRIPTION REGULATOR | |||||
Synonym(s) |
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Gene Symbol | EHMT2 | |||||
Gene ID | 10919 | |||||
Pfam ID | PF12796, PF05033, PF00856 | |||||
Interpro ID | IPR002110, IPR020683, IPR036770, IPR043550, IPR038034, IPR007728, IPR001214 |
Bound Ligands |
HET ID | Ligand Type | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
CIQ | Small Molecule | 3RJW | Ki : 3.7 nM, Ki : 81.0 nM, Ki : 120.0 nM, Ki : 2.5 nM, Ki : 610.0 nM, Ki : 12.0 nM, IC50 : 48.0 nM, IC50 : 210.0 nM, IC50 : 15.0 nM, IC50 : 55.0 nM, IC50 : 59.0 nM, IC50 : 240.0 nM, IC50 : 70.0 nM | BindingDB | SHOW | |
2OD | Small Molecule | 4NVQ | IC50 : 3.3 nM, IC50 : 3.0 nM | BindingDB | SHOW | |
2OD | Small Molecule | 4NVQ | IC50 : 3.3 nM | Binding MOAD | SHOW |