Protein

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Protein Name Histone-lysine N-methyltransferase EHMT2
#PDB ID 2
Organism Homo sapiens
Uniprot ID/ACC Q96KQ7 (EHMT2_HUMAN)
Protein Sequence MAAAAGAAAAAAAEGEAPAEMGALLLEKETRGATERVHGSLGDTPRSEETLPKATPDSLEPAGPSSPASVTVTVGDEGADTPVGATPLIGDESENLEGDGDLRGGRILLGHATKSFPSSPSKGGSCPSRAKMSMTGAGKSPPSVQSLAMRLLSMPGAQGAAAAGSEPPPATTSPEGQPKVHRARKTMSKPGNGQPPVPEKRPPEIQHFRMSDDVHSLGKVTSDLAKRRKLNSGGGLSEELGSARRSGEVTLTKGDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRKRRKREPPRAKEPRGVNGVGSSGPSEYMEVPLGSLELPSEGTLSPNHAGVSNDTSSLETERGFEELPLCSCRMEAPKIDRISERAGHKCMATESVDGELSGCNAAILKRETMRPSSRVALMVLCETHRARMVKHHCCPGCGYFCTAGTFLECHPDFRVAHRFHKACVSQLNGMVFCPHCGEDASEAQEVTIPRGDGVTPPAGTAAPAPPPLSQDVPGRADTSQPSARMRGHGEPRRPPCDPLADTIDSSGPSLTLPNGGCLSAVGLPLGPGREALEKALVIQESERRKKLRFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLGVGNRAIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQSRLARLDPHPELLPELGSLPPVNT
Protein Class TRANSCRIPTION REGULATOR
Synonym(s)
  •   histone-lysine N-methyltransferase EHMT2
  • G9A histone methyltransferase
  • H3-K9-HMTase 3
  • HLA-B associated transcript 8
  • ankyrin repeat-containing protein
  • euchromatic histone-lysine N-methyltransferase 2
  • histone H3-K9 methyltransferase 3
  • histone-lysine N-methyltransferase, H3 lysine-9 specific 3
  • lysine N-methyltransferase 1C
  • BAT8
  • C6orf30
  • G9A
  • GAT8
  • KMT1C
  • NG36
show 14 synonym(s)
Gene Symbol EHMT2
Gene ID 10919
Pfam ID PF12796, PF05033, PF00856
Interpro ID IPR002110, IPR020683, IPR036770, IPR043550, IPR038034, IPR007728, IPR001214
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
CIQ Small Molecule 3RJW Ki : 3.7 nM, Ki : 81.0 nM, Ki : 120.0 nM, Ki : 2.5 nM, Ki : 610.0 nM, Ki : 12.0 nM, IC50 : 48.0 nM, IC50 : 210.0 nM, IC50 : 15.0 nM, IC50 : 55.0 nM, IC50 : 59.0 nM, IC50 : 240.0 nM, IC50 : 70.0 nM BindingDB SHOW
2OD Small Molecule 4NVQ IC50 : 3.3 nM, IC50 : 3.0 nM BindingDB SHOW
2OD Small Molecule 4NVQ IC50 : 3.3 nM Binding MOAD SHOW