Protein

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Protein Name C-C chemokine receptor type 2
#PDB ID 1
Organism Homo sapiens
Uniprot ID/ACC P41597 (CCR2_HUMAN)
Protein Sequence MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTKCQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRGKGKSIGRAPEASLQDKEGA
Protein Class SIGNALING PROTEIN
Synonym(s)
  •   MCP-1 receptor
  • chemokine (C-C motif) receptor 2
  • monocyte chemoattractant protein 1 receptor
  • monocyte chemotactic protein 1 receptor
  • CC-CKR-2
  • CCR-2
  • CCR2A
  • CCR2B
  • CD192
  • CKR2
  • CKR2A
  • CKR2B
  • CMKBR2
  • MCP-1-R
show 13 synonym(s)
Gene Symbol CCR2
Gene ID 729230
Pfam ID PF00001
Interpro ID IPR002237, IPR000355, IPR000276, IPR017452
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
73R Small Molecule 5T1A IC50 : 0.24 nM, IC50 : 0.7 nM, IC50 : 4.7 nM BindingDB SHOW