Protein

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Protein Name E3 ubiquitin-protein ligase UHRF1
#PDB ID 5
Organism Homo sapiens
Uniprot ID/ACC Q96T88 (UHRF1_HUMAN)
Protein Sequence MWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFYRGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKSSTHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRDEPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGSPMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDPPLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRTKECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDWRSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEPGPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKWKRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPASGSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLGRSYAMQVNQPLQTVLNQLFPGYGNGR
Protein Class LIGASE
Synonym(s)
  •   RING finger protein 106
  • RING-type E3 ubiquitin transferase UHRF1
  • inverted CCAAT box-binding protein of 90 kDa
  • nuclear phosphoprotein 95
  • nuclear protein 95
  • nuclear zinc finger protein Np95
  • transcription factor ICBP90
  • ubiquitin-like PHD and RING finger domain-containing protein 1
  • ICBP90
  • Np95
  • RNF106
  • TDRD22
  • hNP95
  • hUHRF1
  • huNp95
show 14 synonym(s)
Gene Symbol UHRF1
Gene ID 29128
Pfam ID PF00628, PF02182, PF12148, PF00240
Interpro ID IPR015947, IPR036987, IPR003105, IPR021991, IPR000626, IPR029071, IPR011011, IPR001965, IPR019787, IPR001841, IPR013083, IPR017907
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
M3L LIG1-K126me3 5YY9
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SHOW
36X Small Molecule 4QQD
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SHOW
M3L H3K9me3 3DB3
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SHOW
M3L H3K9me3 3ASK
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SHOW
M3L H3K9me3 4GY5
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SHOW