Protein

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Protein Name Histone-lysine N-methyltransferase SETDB1
#PDB ID 4
Organism Homo sapiens
Uniprot ID/ACC Q15047 (SETB1_HUMAN)
Protein Sequence MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQLAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPTEIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDLHKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRPNMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSDLESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAPSALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVPPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRMEAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKTSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSGSEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
Protein Class TRANSCRIPTION REGULATOR
Synonym(s)
  •   histone-lysine N-methyltransferase SETDB1
  • ERG-associated protein with a SET domain, ESET
  • SET domain bifurcated 1
  • histone H3-K9 methyltransferase 4
  • histone-lysine N-methyltransferase, H3lysine-9 specific 4
  • lysine N-methyltransferase 1E
  • tudor domain containing 21
  • ESET
  • H3-K9-HMTase4
  • KG1T
  • KMT1E
  • TDRD21
show 11 synonym(s)
Gene Symbol SETDB1
Gene ID 9869
Pfam ID PF18300, PF01429, PF05033, PF00856, PF18358, PF18359
Interpro ID IPR016177, IPR040880, IPR025796, IPR001739, IPR003616, IPR007728, IPR001214, IPR002999, IPR041292, IPR041291
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
MLY H3K9me2 6BPI
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SHOW
M3L H3K9me3 6BHE
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SHOW
MLY H3K9me2 6BHD
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SHOW
M3L H3K9me3 6BHI
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SHOW