Protein

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Protein Name High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
#PDB ID 1
Organism Homo sapiens
Uniprot ID/ACC O76083 (PDE9A_HUMAN)
Protein Sequence MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Protein Class HYDROLASE
Synonym(s)
  •   high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
  • CGMP-specific 3',5'-cyclic phosphodiesterase type 9
  • phosphodiesterase PDE9A21
  • HSPDE9A2
show 3 synonym(s)
Gene Symbol PDE9A
Gene ID 5152
Pfam ID PF00233
Interpro ID IPR003607, IPR023088, IPR002073, IPR036971, IPR023174
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
49D Small Molecule 4Y86 IC50 : 11.0 nM Binding MOAD SHOW