Protein

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Protein Name Glycine receptor subunit alpha-3
#PDB ID 1
Organism Homo sapiens
Uniprot ID/ACC O75311 (GLRA3_HUMAN)
Protein Sequence MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
Protein Class SIGNALING PROTEIN
Synonym(s)
  •   glycine receptor subunit alpha-3
  • glycine receptor, alpha-3 polypeptide
  • ligand gated ion channel
show 2 synonym(s)
Gene Symbol GLRA3
Gene ID 8001
Pfam ID PF02931, PF02932
Interpro ID IPR006028, IPR008127, IPR008130, IPR006202, IPR036734, IPR006201, IPR036719, IPR006029, IPR018000
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
SY9 Small Molecule 5CFB Ki : 12.0 nM, Ki : 23.0 nM, Ki : 180.0 nM, IC50 : 182.0 nM, IC50 : 93.0 nM, IC50 : 58.0 nM, IC50 : 51.0 nM BindingDB SHOW