Protein

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Protein Name 5-hydroxytryptamine receptor 3A
#PDB ID 3
Organism Mus musculus
Uniprot ID/ACC P23979 (5HT3A_MOUSE)
Protein Sequence MRLCIPQVLLALFLSMLTAPGEGSRRRATQEDTTQPALLRLSDHLLANYKKGVRPVRDWRKPTTVSIDVIMYAILNVDEKNQVLTTYIWYRQYWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVHHRGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINITLWRSPEEVRSDKSIFINQGEWELLEVFPQFKEFSIDISNSYAEMKFYVIIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQRPVPDWLRHLVLDRIAWILCLGEQPMAHRPPATFQANKTDDCSGSDLLPAMGNHCSHVGGPQDLEKTPRGRGSPLPPPREASLAVRGLLQELSSIRHFLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS
Protein Class SIGNALING PROTEIN
Synonym(s)
  •   5-hydroxytryptamine receptor 3
  • 5HT3 serotonin receptor
  • serotonin receptor 3A
  • serotonin-gated ion channel receptor
  • 5-HT3
  • 5-HT3A
  • 5-HT3R
show 6 synonym(s)
Gene Symbol Htr3a
Gene ID 15561
Pfam ID PF02931, PF02932
Interpro ID IPR008132, IPR008133, IPR006202, IPR036734, IPR006201, IPR036719, IPR006029, IPR018000
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
O7B Small Molecule 6Y1Z Kd : 0.32 nM, Kd : 0.18 nM, Ki : 0.03 nM, Ki : 0.04 nM, IC50 : 0.83 nM, IC50 : 0.88 nM BindingDB SHOW
TKT Small Molecule 6HIS
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SHOW
CWB Small Molecule 6NP0
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SHOW