Protein

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Protein Name Interleukin-1 receptor-associated kinase 4
#PDB ID 1
Organism Homo sapiens
Uniprot ID/ACC Q9NWZ3 (IRAK4_HUMAN)
Protein Sequence MNKPITPSTYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTGKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSKEAITVQQKQMPFCDKDRTLMTPVQNLEQSYMPPDSSSPENKSLEVSDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS
Protein Class HYDROLASE
Synonym(s)
  •   interleukin-1 receptor-associated kinase 4
  • renal carcinoma antigen NY-REN-64
  • IMD67
  • IPD1
  • IRAK-4
  • NY-REN-64
  • REN64
show 6 synonym(s)
Gene Symbol IRAK4
Gene ID 51135
Pfam ID PF07714
Interpro ID IPR011029, IPR017428, IPR037970, IPR011009, IPR000719, IPR001245
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
0LI Small Molecule 6EG9 IC50 : 66.9 nM Binding MOAD SHOW