Protein

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Protein Name Acetylcholinesterase
#PDB ID 14
Organism Homo sapiens
Uniprot ID/ACC P22303 (ACES_HUMAN)
Protein Sequence MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL
Protein Class HYDROLASE
Synonym(s)
  •   acetylcholinesterase
  • Yt blood group
  • acetylcholinesterase (Yt blood group)
  • apoptosis-related acetylcholinesterase
  • ACEE
  • ARACHE
  • N-ACHE
  • YT
show 7 synonym(s)
Gene Symbol ACHE
Gene ID 43
Pfam ID PF08674, PF00135
Interpro ID IPR029058, IPR014788, IPR002018, IPR019826, IPR019819, IPR000997
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
E20 Small Molecule 4EY7 IC50 : 5.3 nM, IC50 : 120.0 nM, IC50 : 160.0 nM, IC50 : 26.8 nM, IC50 : 5.0 nM, IC50 : 8.2 nM, IC50 : 2.0 nM, IC50 : 6.9 nM, IC50 : 3.5 nM, IC50 : 13.0 nM, IC50 : 1.7 nM, IC50 : 0.12 nM, IC50 : 11.0 nM, IC50 : 12.0 nM, IC50 : 7.9 nM, IC50 : 35.48 nM, IC50 : 19.0 nM, IC50 : 20.0 nM, IC50 : 6.0 nM, IC50 : 4.2 nM, IC50 : 15.0 nM, IC50 : 16.0 nM, IC50 : 7.0 nM, IC50 : 2.3 nM, IC50 : 23.1 nM, IC50 : 8.0 nM, IC50 : 21.5 nM, IC50 : 22.0 nM, IC50 : 9.0 nM, IC50 : 19.0 nM, IC50 : 10.0 nM, IC50 : 8.12 nM, IC50 : 11.0 nM, IC50 : 37.0 nM, IC50 : 40.0 nM, IC50 : 12.0 nM, IC50 : 32.0 nM, IC50 : 14.0 nM, IC50 : 15.0 nM, IC50 : 16.0 nM, IC50 : 18.0 nM, IC50 : 19.0 nM, EC50 : 43.0 nM, IC50 : 20.0 nM, IC50 : 22.0 nM, IC50 : 23.0 nM, IC50 : 6.0 nM, IC50 : 30.0 nM, IC50 : 32.0 nM, IC50 : 36.0 nM, IC50 : 38.0 nM, IC50 : 94.0 nM, IC50 : 40.0 nM, IC50 : 41.0 nM, IC50 : 48.0 nM, IC50 : 50.0 nM, IC50 : 6.16 nM, IC50 : 5.7 nM, IC50 : 5.7 nM, IC50 : 11.6 nM, IC50 : 0.02 nM, IC50 : 62.0 nM, IC50 : 8.0 nM, IC50 : 90.0 nM, Ki : 2.9 nM, Ki : 38.0 nM, Ki : 7.2 nM, Ki : 10.0 nM, Ki : 20.5 nM, Ki : 21.0 nM, Ki : 2.9 nM, Ki : 26.0 nM BindingDB SHOW
E20 Small Molecule 6O4W
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-
SHOW
HI6 Small Molecule 6NTM
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SHOW
L0S Small Molecule 6NTH
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SHOW
EBW Small Molecule 6O52
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SHOW
PQY Small Molecule 6U3P
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SHOW
PQV Small Molecule 6U34
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SHOW
L2Y Small Molecule 6NTO
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SHOW
HLO Small Molecule 6NEA
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SHOW
HI6 Small Molecule 6NTN
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SHOW
EBW Small Molecule 6O50
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SHOW
L0S Small Molecule 6NTK
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SHOW
HI6 Small Molecule 6NTG
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SHOW
L1M Small Molecule 6NTL
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SHOW