Protein

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Protein Name Tissue-type plasminogen activator
#PDB ID 2
Organism Homo sapiens
Uniprot ID/ACC P00750 (TPA_HUMAN)
Protein Sequence MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP
Protein Class HYDROLASE
Synonym(s)
  •   tissue-type plasminogen activator
  • alteplase
  • plasminogen/activator kringle
  • reteplase
  • t-plasminogen activator
  • T-PA
  • TPA
show 6 synonym(s)
Gene Symbol PLAT
Gene ID 5327
Pfam ID PF00008, PF00039, PF00051, PF00089
Interpro ID IPR000742, IPR000083, IPR000001, IPR013806, IPR018056, IPR038178, IPR009003, IPR043504, IPR001314, IPR026280, IPR034811, IPR001254, IPR018114, IPR033116
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
ACA Small Molecule 1PK2
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ACA Small Molecule 6DCM
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